Human Albumin 20% Injection 100ml

• What it is: A solution containing 20 grams of human albumin in 100ml of electrolyte solution. Albumin is a natural protein found in the blood that helps regulate fluid balance by maintaining osmotic pressure.
• What it does: The 20% solution is hyperoncotic, meaning it can draw fluid from the body's tissues into the bloodstream to increase circulating blood volume. This helps to raise and stabilize blood pressure and improve circulation. 

• Shock and trauma: To replace lost body fluids after major trauma, bleeding, surgery,burns.
• Liver cirrhosis: To prevent complications after the removal of large amounts of fluid (paracentesis) from the abdomen.
• Adult Respiratory Distress Syndrome (ARDS): Used in conjunction with diuretics to manage fluid overload.
• Nephrotic syndrome: To treat swelling (edema) that does not respond to other therapies.
• Hemolytic disease of the newborn: Used to manage high bilirubin levels.
• Ovarian Hyperstimulation Syndrome (OHSS): Used as a plasma volume expander. 

• Administration: It is administered as a slow intravenous infusion by a medical professional. For patients with normal blood volume, the infusion rate should not exceed 1ml per minute to prevent circulatory overload.
• Dosage: The dose and rate of infusion are tailored to the patient's specific needs, size, and condition.
• Dilution: It can be administered undiluted or diluted in an isotonic solution like 0.9% sodium chloride. It must not be diluted with sterile water, as this can cause the patient's red blood cells to burst (hemolysis). 

• A history of allergy or hypersensitivity to albumin preparations.
• Severe anemia.
• Cardiac failure with normal or increased blood volume, as it can worsen fluid overload.
• Severe pulmonary edema.
• Traumatic brain injury, where it is associated with increased mortality.
• Hepatic failure with cirrhosis and ascites, except for certain specific indications. 

• Flushing (reddening of the face, neck, and trunk)
• Chills and fever
• Nausea and vomiting
• Hives and rashes
• Allergic reactions, including rare cases of anaphylactic shock.
• Circulatory overload (hypervolemia), especially with rapid infusion. Symptoms may include headache, difficult breathing, and a rapid heartbeat. 

• The product should be stored as directed by the manufacturer, typically at a temperature of 2–8°C (refrigerated), or sometimes below 30°C, depending on the brand.
• It should not be frozen.
• The solution should be clear or slightly pearlescent. Do not use if it is cloudy or has deposits.
• Once opened, any unused portion must be discarded, as the solution contains no antimicrobial preservatives. 

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